background:
EBNA 3B is one of only 10 viral proteins expressed in Epstein Barr Virus (EBV) transformed B lymphoblasts cultured in vitro, though the expression of EBNA 3B is not required for EBSLVmediated transformation in vitro. This 165kDa nuclear protein functions as a transcription factor.
Function:
May be involved in transcriptional regulation of both viral and cellular genes by interacting with the host DNA-binding protein RBPJ.
Subunit:
Interacts (via N-terminus) with host RBPJ.
Subcellular Location:
Host nucleus.
Similarity:
Belongs to the herpesviridae EBNA-4 family.
Database links:
UniProtKB/Swiss-Prot: P0643.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
EB病毒核抗原-3（nuclear antigen EBNA-3）是EB病毒编码核蛋白，位于细胞核的新的酶聚合体，主要作为转录调节因子，指导蛋白与蛋白之间相互作用，为核糖核苷酸补救途径的一部分.
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