Rabbit Anti-BXDC2/FITC Conjugated antibody

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BRIX; Brix domain containing 2; Brix domain containing protein 2; BRIX1; BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); FLJ11100; Ribosome biogenesis protein Brix; BRX1_HUMAN.

Cat:

SL8436R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human BXDC2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

41kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.

Function:
Required for biogenesis of the 60S ribosomal subunit.

Subcellular Location:
Nucleus, nucleolus.

Similarity:
Belongs to the BRX1 family.
Contains 1 Brix domain.

Database links:

Entrez Gene: 55299 Human

Entrez Gene: 67832 Mouse

SwissProt: Q3SZZ0 Cow

SwissProt: Q8TDN6 Human

SwissProt: Q9DCA5 Mouse

Unigene: 718510 Human

Unigene: 28057 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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