Rabbit Anti-HHLA2/FITC Conjugated antibody

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Human endogenous retrovirus H long terminal repeat associating protein 2; HERV H LTR associating 2; HERV-H LTR-associating protein 2; HHLA 2; HHLA2; HHLA2_HUMAN; Human endogenous retrovirus-H long terminal repeat-associating protein 2.

Cat:

SL8419R-FITC

Species Reactivity：

Human,

Immunogen：

KLH conjugated synthetic peptide derived from human HHLA2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Human endogenous retroviruses (HERVs) are repetitive elements that are derived from ancient germline retroviral infections. Due to their ability to move and insert next to certain genes and alter expression patterns, HERVs have been linked to several chronic diseases such as nervous systemic diseases, cancer, autoimmune and connective tissue diseases. The HERSLVH family is the most abundant HERV family and has been implicated in the expression of a variety of adjacent genes. Proteins belonging to the HERSLVH family are divided into one major and two minor groups based on sequence divergence. As a member of the HERSLVH family, HHLA2 (HERSLVH LTR-associating protein 2) is a 414 amino acid single-pass type I membrane protein that contains one Ig-like C1-type (immunoglobulin-like) domain and two Ig-like SLVtype (immunoglobulin-like) domains. HHLA2 is primarily expressed in kidney, lung and intestinal tissues.

Subcellular Location:
Membrane; Single-pass type I membrane protein (By similarity).

Tissue Specificity:
Expressed in colon, small intestine, lung and kidney.

Similarity:
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
Contains 2 Ig-like SLVtype (immunoglobulin-like) domains.

Database links:

Entrez Gene: 11148 Human

Omim: 604371 Human

SwissProt: Q9UM44 Human

Unigene: 252351 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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