background:
Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum.
Function:
Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Similarity:
Belongs to the ubiquitin-conjugating enzyme family.
Database links:
UniProtKB/Swiss-Prot: Q9Y385.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|