background:
PANK4 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the physiological regulation of the intracellular coenzyme A (CoA) concentration. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.
Function:
Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).
Subunit:
Homodimer. Interacts with PKM (By similarity).
Subcellular Location:
Cytoplasm (Probable).
Tissue Specificity:
Ubiquitously expressed with higher expression in the muscle.
Similarity:
Belongs to the type II pantothenate kinase family.
Database links:
UniProtKB/Swiss-Prot: Q9NVE7.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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