Home > Product > Antibody > Rabbit Anti-PANK4/FITC Conjugated antibody
DKFZp547M242; FLJ10782; hPanK 4; hPanK4; PANK 4; Pantothenate kinase 4; Pantothenic acid kinase; PANK4_HUMAN.
Cat:
SL8340R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from human PANK4
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
86kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
PANK4 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the physiological regulation of the intracellular coenzyme A (CoA) concentration. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.

Function:
Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).

Subunit:
Homodimer. Interacts with PKM (By similarity).

Subcellular Location:
Cytoplasm (Probable).

Tissue Specificity:
Ubiquitously expressed with higher expression in the muscle.

Similarity:
Belongs to the type II pantothenate kinase family.

Database links:
UniProtKB/Swiss-Prot: Q9NVE7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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