background:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Function:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Subunit:
Interacts with CCDC64/BICDR1; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with RAB6KIFL. Interacts (GTP-bound) with BICD1 (via SLCterminus); the interaction is direct. Interacts (GDP-bound) with DYNLRB1.
Subcellular Location:
Golgi apparatus membrane. Cytoplasmic vesicle. Colocalizes with BICD1 at vesicular structures that align along microtubules.
Tissue Specificity:
Predominantly expressed in brain.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
Database links:
UniProtKB/Swiss-Prot: Q9NRW1.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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