Rabbit Anti-RAB40B/FITC Conjugated antibody

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SEC4L; GTP binding protein homologous to Saccharomyces cerevisiae SEC4; RAB40B member RAS oncogene family; RAR; Rar protein; Ras related protein Rab 40B; RP23 293H17.2; SOCS box containing protein RAR; FLJ42385; RB40B_HUMAN.

Cat:

SL8365R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human RAB40B

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

31kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
RAB40B is similar to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. It may be a substrate recognition component of a SCF like ECS (Elongin Cullin SOCS box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Function:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Subcellular Location:
Cell membrane; Lipid anchor; Cytoplasmic side.

Similarity:
Belongs to the small GTPase superfamily. Rab family.
Contains 1 SOCS box domain.

Database links:

Entrez Gene: 10966 Human

Entrez Gene: 217371 Mouse

Entrez Gene: 303754 Rat

SwissProt: Q12829 Human

SwissProt: Q8VHP8 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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