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Rabbit Anti-ZnT-1/FITC Conjugated antibody
background:
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a SLCterminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells.
Function:
May be involved in zinc transport out of the cell.
Subunit:
Multimer.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Database links:
Entrez Gene: 7779 Human
Entrez Gene: 22782 Mouse
Entrez Gene: 58976 Rat
Omim: 609521 Human
SwissProt: Q9Y6M5 Human
SwissProt: Q60738 Mouse
SwissProt: Q62720 Rat
Unigene: 519469 Human
Unigene: 9024 Mouse
Unigene: 10120 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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