Home > Product > Antibody > Rabbit Anti-DHPS1/FITC Conjugated antibody
dehydrogenase/reductase (SDR family) member 1; Dehydrogenase/reductase SDR family member 1; FLJ25430; MGC20204; DHRS1_HUMAN.
Cat:
SL8260R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from human DHPS1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
34kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
DHRS1 (dehydrogenase/reductase (SDR family) member 1), also known as SDR19C1, is a 313 amino acid protein that belongs to the short-chain dehydrogenases/reductases (SDR) family and likely functions as an oxidoreductase. Abundantly expressed in heart and liver, DHRS1 contains an SDR motif and is encoded by a gene that maps to human chromosome 14q12. Human chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Tissue Specificity:
Detected in heart and liver, and at low levels in skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links:
UniProtKB/Swiss-Prot: Q96LJ7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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