Rabbit Anti-Lens culinaris agglutinin/FITC Conjugated antibody

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LCA/Lens culinaris agglutinin; LEC_LENCU.

Cat:

SL6439R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from Lens culinaris agglutinin

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

27kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are engulfed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. Although LCA and LCB are encoded by two discrete genes sharing only 60% homology, they have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms. Additionally, in the brain, LCA and LCB contain inserted sequences that form higher molecular weight isoforms. These sequences insert at similar cytoplasmic domain encoding regions for both LCA and LCB.

Similarity:
Belongs to the leguminous lectin family.

Database links:

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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