background:
FRMD3 is a multifunctional protein essential for maintaining erythrocyte shape and membrane mechanical properties. Is a putative tumor suppressor gene. 5 different isoforms generated by alternative splicing have been described.
Function:
Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.
Subcellular Location:
Membrane; Single-pass membrane protein (Potential).
Tissue Specificity:
Ovary-specific.
Similarity:
Contains 1 FERM domain.
Database links:
Entrez Gene: 533321 Cow
Entrez Gene: 484151 Dog
Entrez Gene: 100726134 Guinea pig
Entrez Gene: 100054067 Horse
Entrez Gene: 257019 Human
Entrez Gene: 242506 Mouse
Entrez Gene: 100519727 Pig
Entrez Gene: 298141 Rat
Omim: 607619 Human
SwissProt: A2A2Y4 Human
SwissProt: Q8SHD4 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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