Home > Product > Antibody > Rabbit Anti-FAM161B/FITC Conjugated antibody
C14orf44; Chromosome 14 open reading frame 44; Family with sequence similarity 161, member B; FLJ31697; Hypothetical protein LOC145483; Protein FAM161B; F161B_HUMAN.
Cat:
SL8226R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human FAM161B
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
74kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.

Subunit:
Interacts with FAM161A.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the FAM161 family.

Database links:
UniProtKB/Swiss-Prot: Q96MY7.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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