background:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
Function:
Component of the core-TFIIH basal transcription factorinvolved in nucleotide excision repair (NER) of DNA and, whencomplexed to CAK, in RNA transcription by RNA polymerase II.
Subunit:
One of the 6 subunits forming the core-TFIIH basaltranscription factor which associates with the CAK complex composedof CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basaltranscription factor. Interacts with PUF60.
Subcellular Location:
Nucleus.
Similarity:
Contains 2 BSD domains.
Database links:
UniProtKB/Swiss-Prot: P32780.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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