Rabbit Anti-CBX1/FITC Conjugated antibody

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HP1 beta; CBX 1; CBX; CBX; CBX-1; CBX1_HUMAN; chromobox homolog 1; chromobox homolog 1; Chromobox protein homolog 1; Drosophila HP1 beta; Drosophila HP1 beta; Heterochromatin protein 1 homolog beta; Heterochromatin protein p25; heterochromatin protein p25

Cat:

SL8169R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human CBX1/HP1 beta

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

21kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Tissue specificity: Expressed in all adult and embryonic tissues.

Function:
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.

Subunit:
Homodimer.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in all adult and embryonic tissues.

Similarity:
Contains 2 chromo domains.

Database links:
UniProtKB/Swiss-Prot: P83916.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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