background:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Function:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Subunit:
Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HISLV1 Vpr. Interacts with GPBP1 (By similarity). Interacts with Epstein-Barr virus EBNA2.
Subcellular Location:
Nucleus
Similarity:
Belongs to the TFIIB family.
Contains 1 TFIIB-type zinc finger.
Database links:
UniProtKB/Swiss-Prot: Q00403.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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