background:
Most abundant in pineal gland, less in retina and brain, not in pigment epithelium.
Function:
Produces melatonin (N-acetyl-5-methoxytryptamine) from N-acetylserotonin.
Tissue Specificity:
Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level (PubMed:7989373), and not at the protein level (PubMed:8574683).
Similarity:
Belongs to the methyltransferase superfamily.
Database links:
UniProtKB/Swiss-Prot: P46597.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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