Rabbit Anti-HCV NS5A transactivated protein 8/FITC Conjugated antibody

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BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.

Cat:

SL8158R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human BTBD1/HCV NS5A transactivated protein 8

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

53kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The SLCterminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.

Function:
Probable substrate-specific adapter of an E3ubiquitin-protein ligase complex which mediates the ubiquitinationand subsequent proteasomal degradation of target proteins.

Subunit:
Interacts with topoisomerase 1 and with TRIM5 isoformDelta. Interacts with CUL3.

Subcellular Location:
Cytoplasm, P-body. Note=Cytoplasmic bodies.

Tissue Specificity:
Ubiquitous; higher levels in heart andskeletal muscle.

Similarity:
Contains 1 BTB (POZ) domain.

Database links:
UniProtKB/Swiss-Prot: Q9H0C5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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