background:
BTBD10 appears to behave as a suppressor of cell death, which includes neuronal cell death related to amyotrophic lateral sclerosis. It may also act as an enhancer of cell growth via its positive regulation of Akt phosphorylation.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitously expressed. Highly expressed inadult brain, testis and small intestine and weakly expressed in theheart, lung, liver, kidney, pancreas, spleen, thymus, prostate,ovary and colon. Down-regulated in glioma.
Similarity:
Contains 1 BTB (POZ) domain.
Database links:
UniProtKB/Swiss-Prot: Q9BSF8.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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