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Rabbit Anti-SNX27/FITC Conjugated antibody
background:
SNX27 is involved in endocytic trafficking. In T lymphocytes it participates in the endocytic recycling pathway. SNX27 recruits PSCDBP and HT4R to early endosomes.
Function:
Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity).
Subunit:
Interacts with PSCDBP. Isoforms 1 and 2 directly interact with DGKZ. Isoforms 1 and 2 interact with HT4R isoform 5-HTA(A). Interacts with MCC.
Subcellular Location:
Cytoplasm, cytosol. Early endosome. Note=In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
Tissue Specificity:
Expressed in cells of hematopoietic origin (at protein level).
Similarity:
Belongs to the sorting nexin family.
Contains 1 PDZ (DHR) domain.
Contains 1 PX (phox homology) domain.
Contains 1 Ras-associating domain.
Database links:
Entrez Gene: 81609 Human
Omim: 611541 Human
SwissProt: Q96L92 Human
Unigene: 192326 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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