Home > Product > Antibody > Rabbit Anti-CCDC42/FITC Conjugated antibody
CCDC42A; Coiled coil domain containing 42; Coiled coil domain containing protein 42A; FLJ32734; OTTMUSP00000006142; RGD1565925; RP23-400O5.1; CCD42_HUMAN.
Cat:
SL8131R-FITC
Species Reactivity:
Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human CCDC42
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
38kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC42 (coiled-coil domain containing 42) is a 316 amino acid protein encoded by a gene that maps to human chromosome 17p13.1. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.

Similarity:
Belongs to the CFAP73 family.

Database links:

Entrez Gene: 146849 Human

Entrez Gene: 276920 Mouse

Entrez Gene: 303234 Rat

SwissProt: Q96M95 Human

SwissProt: Q5SV66 Mouse

Unigene: 71842 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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