Rabbit Anti-AGFG1/FITC Conjugated antibody

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HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-lik

Cat:

SL8072R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human AGFG1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

58kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HISLV1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HISLV1 replication.

Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HISLV1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HISLV1 replication.

Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.

Subcellular Location:
Nucleus. Cytoplasmic vesicle.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
O-glycosylated (By similarity).

Similarity:
Contains 1 Arf-GAP domain.

Database links:

Entrez Gene: 536149 Cow

Entrez Gene: 3267 Human

Entrez Gene: 15463 Mouse

Entrez Gene: 363266 Rat

Omim: 600862 Human

SwissProt: Q2TA45 Cow

SwissProt: P52594 Human

SwissProt: Q8K2K6 Mouse

SwissProt: Q4KLH5 Rat

Unigene: 352962 Human

Unigene: 392569 Mouse

Unigene: 433409 Mouse

Unigene: 3734 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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