background:
GABARAPL1 belongs to the MAP1 LC3 family. It increases cell surface expression of kappa type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.
Subunit:
Interacts with GABRG2 and beta-tubulin. Interacts with OPRK1.
Subcellular Location:
Cytoplasm, cytoskeleton. Membrane. Endoplasmic reticulum. Golgi apparatus.
Tissue Specificity:
Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine.
Similarity:
Belongs to the MAP1 LC3 family.
Database links:
Entrez Gene: 338472 Cow
Entrez Gene: 612919 Dog
Entrez Gene: 100135524 Guinea pig
Entrez Gene: 23710 Human
Entrez Gene: 57436 Mouse
Entrez Gene: 100462751 Pig
Entrez Gene: 689161 Rat
Omim: 607420 Human
SwissProt: Q8HYB6 Cow
SwissProt: P60518 Guinea pig
SwissProt: Q9H0R8 Human
SwissProt: Q8R3R8 Mouse
SwissProt: Q0VGK0 Rat
Unigene: 524250 Human
Unigene: 14638 Mouse
Unigene: 118264 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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