Rabbit Anti-CNKSR1/FITC Conjugated antibody

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CNK； CNK homolog protein 1； CNK1； CNKR1_HUMAN； CNKSR1； Connector enhancer of kinase suppressor of ras 1； Connector enhancer of KSR 1； Connector enhancer of KSR like； Connector enhancer of KSR-like； Connector enhancer of KSR1； hCNK1； KSR.

Cat:

SL8028R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human CNKSR1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

80kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway. [provided by RefSeq, Jul 2008].

Function:
May function as an adapter protein or regulator of Ras signaling pathways.

Subunit:
Interacts with RHO and RALGDS.

Subcellular Location:
Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).

Post-translational modifications:
Phosphorylated on tyrosine.

Similarity:
Belongs to the CNKSR family.
Contains 1 CRIC domain.
Contains 1 PDZ (DHR) domain.
Contains 1 PH domain.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 10256 Human

Entrez Gene: 194231 Mouse

Entrez Gene: 298545 Rat

Omim: 603272 Human

SwissProt: Q969H4 Human

Unigene: 16232 Human

Unigene: 726160 Human

Unigene: 331958 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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