Rabbit Anti-CCDC52/FITC Conjugated antibody

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Coiled coil domain containing protein 52; Coiled-coil domain-containing protein 52; FLJ26064; FLJ44949; SPICE_HUMAN; spice1; Spindle and centriole-associated protein 1; Spindle and centriole-associated protein.

Cat:

SL7989R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human CCDC52

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

96kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. The gene encoding CCDC52 (Coiled-coil domain-containing protein 52), a 855 amino acid protein, exists on human chromosome 3.

Function:
Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.

Subunit:
Interacts with CEP120

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.

Database links:

Entrez Gene: 152185 Human

Omim: 613447 Human

SwissProt: Q8N0Z3 Human

Unigene: 477144 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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