Rabbit Anti-ANKS1A/FITC Conjugated antibody

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ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1; Ankyrin repeat and SAM domain containing protein 1A; Ankyrin repeat and SAM domain-containing protein 1A; Ankyrin repeat and sterile alpha motif domain containing 1A; ANS1A_HUMAN;

Cat:

SL7966R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ANKS1A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

123kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
May play a negative role in growth factor receptor signaling pathways.

Function:
Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction.

Subunit:
Interacts with EPHA8; EPHA8 kinase activity-independent but stimulated by EPHA8 ubiquitination.

Subcellular Location:
Cytoplasm. Cell projection. Note=Cytoplasmic before and after growth factor treatment.

Tissue Specificity:
Widely expressed (at protein level).

Post-translational modifications:
Phosphorylated on tyrosine residues in response to EGF and PDGF.

Similarity:
Contains 6 ANK repeats.
Contains 1 PID domain.
Contains 2 SAM (sterile alpha motif) domains.

Database links:

Entrez Gene: 23294 Human

Entrez Gene: 224650 Mouse

Entrez Gene: 309639 Rat

Omim: 608994 Human

SwissProt: Q92625 Human

SwissProt: P59672 Mouse

Unigene: 656492 Human

Unigene: 32556 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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