background:
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Function:
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Secreted, extracellular space.
Tissue Specificity:
Placenta and kidney.
Post-translational modifications:
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
Similarity:
Belongs to the copper/topaquinone oxidase family.
Database links:
UniProtKB/Swiss-Prot: P3961.4
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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