Rabbit Anti-TPTE/FITC Conjugated antibody

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Cancer/testis antigen 44; CT44; EC=3.1.3.48; HGNC:12023; PTEN2; Putative tyrosine protein phosphatase; Putative tyrosine-protein phosphatase TPTE; TPTE; TPTE_HUMAN; Transmembrane phosphatase with tensin homology; Tumor antigen BJ HCC 5; Tumor antigen BJ-H

Cat:

SL7955R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TPTE

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

64kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
TPTE is a 551 amino acid multi-pass membrane protein belonging to the PTEN-related family that is exclusively expressed in the testis and localizes to the plasma membrane in humans. The gene encoding TPTE is present in multiple copies in the human genome, some of which may be pseudogenes. TPTE contains one C2 tensin-type domain and one phosphatase tensin-type domain but, in humans, it does not exhibit phosphatase activity. However, the mouse ortholog (PTEN2) is a functional 3-phosphoinositide phosphatase that localizes to the Golgi apparatus and plays a possible role in signal transduction. In humans, four isoforms, namely TPTEå, TPTE∫, TPTE© and TPTE∂, are produced by alternative splicing of this gene.

Function:
Could be involved in signal transduction.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Exclusively expressed in testis.

Similarity:
Contains 1 C2 tensin-type domain.
Contains 1 phosphatase tensin-type domain.

Database links:

Entrez Gene: 7179 Human

Omim: 604336 Human

SwissProt: P5636 Human

Unigene: 122986 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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