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Rabbit Anti-PPP2R1B/FITC Conjugated antibody
background:
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
Function:
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
Subunit:
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with IPO9. Interacts with SGOL1. Interacts with RAF1.
Similarity:
Belongs to the phosphatase 2A regulatory subunit A family.
Contains 15 HEAT repeats.
Database links:
Entrez Gene: 5519 Human
Entrez Gene: 73699 Mouse
Entrez Gene: 315648 Rat
Omim: 603113 Human
SwissProt: P30154 Human
SwissProt: Q7TNP2 Mouse
SwissProt: Q4QQT4 Rat
Unigene: 584790 Human
Unigene: 7726 Mouse
Unigene: 163017 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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