Rabbit Anti-SIPA1L2/FITC Conjugated antibody

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SI1L2_HUMAN; Signal induced proliferation associated 1 like protein 2; Signal-induced proliferation-associated 1-like protein 2; SIPA1 like protein 2; SIPA1-like protein 2; SIPA1L2; SPAL2; KIAA1389.

Cat:

SL7927R-FITC

Species Reactivity：

Rat,(predicted: Human,Mouse,Dog,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SIPA1L2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

190kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
SIPA1L2 is a 1,722 amino acid protein that contains one PDZ (DHR) domain and one Rap-GAP domain, and exists as two alternatively spliced isoforms. The gene that encodes SPA-L2 consists of approximately 163,594 bases and maps to human chromosome 1q42.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Similarity:
Contains 1 PDZ (DHR) domain.
Contains 1 Rap-GAP domain.

Database links:

Entrez Gene: 57568 Human

Entrez Gene: 361442 Rat

Omim: 611609 Human

SwissProt: Q9P2F8 Human

SwissProt: Q80TE4 Mouse

SwissProt: Q5JCS6 Rat

Unigene: 268774 Human

Unigene: 271668 Mouse

Unigene: 463243 Mouse

Unigene: 44190 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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