Rabbit Anti-CD20L/MS4A3/FITC Conjugated antibody

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CD20 antigen homolog; CD20 antigen like; CD20 antigen like protein; CD20 antigen-like protein; CD20L; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTm4; IgE receptor beta subunit; Membrane-spanning 4

Cat:

SL7900R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human MS4A3/CD20L

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

23kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
MS4A3 is a member of the membrane-spanning 4A gene family and displays unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A3 is likely to play a role in signal transduction and may function as a subunit associated with receptor complexes. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.

Function:
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).

Subunit:
Interacts with CDKN3. Interacts with CDKN3-CDK2 complexes through its binding to CDKN3; this interaction facilitates dissociation of cyclin A from CDKN3-CDK2 complexes.

Subcellular Location:
Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Located in the perinuclear area.

Tissue Specificity:
Expressed specifically in hematopoietic cells and tissues.

Similarity:
Belongs to the MS4A family.

Database links:

Entrez Gene: 932 Human

Omim: 606498 Human

SwissProt: Q96HJ5 Human

Unigene: 99960 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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