Home
>
Product
>
Antibody
>
Rabbit Anti-CD20L/MS4A3/FITC Conjugated antibody
background:
MS4A3 is a member of the membrane-spanning 4A gene family and displays unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A3 is likely to play a role in signal transduction and may function as a subunit associated with receptor complexes. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.
Function:
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).
Subunit:
Interacts with CDKN3. Interacts with CDKN3-CDK2 complexes through its binding to CDKN3; this interaction facilitates dissociation of cyclin A from CDKN3-CDK2 complexes.
Subcellular Location:
Endomembrane system; Multi-pass membrane protein (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Located in the perinuclear area.
Tissue Specificity:
Expressed specifically in hematopoietic cells and tissues.
Similarity:
Belongs to the MS4A family.
Database links:
Entrez Gene: 932 Human
Omim: 606498 Human
SwissProt: Q96HJ5 Human
Unigene: 99960 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|