Rabbit Anti-ABCA9/FITC Conjugated antibody

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ATP binding cassette A9; ATP binding cassette sub family A (ABC1) member 9; ATP binding cassette sub family A member 9; DKFZp686F2450; EST640918; MGC75415; ABCA9_HUMAN.

Cat:

SL7853R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human ABCA9

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

184kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA9 is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of the ABCA9 gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. ABCA9 May play a role in monocyte differentiation and lipid homeostasis.

Function:
May play a role in monocyte differentiation and lipidhomeostasis.

Subcellular Location:
Membrane; Multi-pass membrane protein(Potential).

Tissue Specificity:
Widely expressed with higher expression inheart.

Similarity:
Belongs to the ABC transporter superfamily. ABCAfamily.
Contains 2 ABC transporter domains.

Database links:

Entrez Gene: 10350 Human

Entrez Gene: 217262 Mouse

Entrez Gene: 287788 Rat

Omim: 612507 Human

SwissProt: Q8IUA7 Human

SwissProt: Q8K449 Mouse

Unigene: 131686 Human

Unigene: 291459 Mouse

Unigene: 98251 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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