Rabbit Anti-SUGT1/FITC Conjugated antibody

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Protein 40 6 3; Protein 40-6-3; Sgt1; SGT1 suppressor of G2 allele of SKP1; SGT1B protein; sugt1; SUGT1_HUMAN; Suppressor of G2 allele of SKP1 homolog; Suppressor of G2 allele of SKP1 S. cerevisiae homolog of.

Cat:

SL7831R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SUGT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

41kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

Function:
May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.

Subunit:
Probably associates with SCF (SKP1-CUL1-F-box protein) complex through interaction with SKP1. Interacts with S100A6. Interacts with HSP90.

Similarity:
Belongs to the SUGT1 family. Contains 1 CS domain. Contains 1 SGS domain. Contains 1 SGS domain.

Database links:
UniProtKB/Swiss-Prot: Q9Y2Z0.3

Entrez Gene: 10910 Human

Entrez Gene: 67955 Mouse

Omim: 604098 Human

SwissProt: Human

SwissProt: Q9Y2Z0 Human

SwissProt: Q9CX34 Mouse

Unigene: 281902 Human

Unigene: 18972 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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