background:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
Function:
Component of the Nup107-160 subcomplex of the nuclearpore complex (NPC). The Nup107-160 subcomplex is required for theassembly of a functional NPC. The Nup107-160 subcomplex is alsorequired for normal kinetochore microtubule attachment, mitoticprogression and chromosome segregation.
Subunit:
Component of the Nup107-160 subcomplex of the nuclearpore complex (NPC). The Nup107-160 subcomplex includes NUP160,NUP133, NUP107, NUP98, NUP85, NUP43, NUP37, SEH1 and SEC13.
Subcellular Location:
Chromosome, centromere, kinetochore.Nucleus, nuclear pore complex.
Similarity:
Contains 4 WD repeats.
Database links:
UniProtKB/Swiss-Prot: Q8NFH4.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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