Rabbit Anti-NSP5/NSP 5 alpha 3 alpha/FITC Conjugated antibody

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Cytokinesis and spindle organization B; NSP 5 alpha 3 alpha; Cytospin B; FLJ36955; HCMOGT 1; NSP; NSP5; Nuclear structure protein 5; SPECC1; Spectrin domain with coiled coils 1; Sperm antigen HCMOGT 1; Sperm antigen with calponin homology and coiled coil

Cat:

SL7816R-FITC

Species Reactivity：

(predicted: Human,Rat,Dog,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human NSP5

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

119kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
NSP type 5 alpha 3 alpha is a novel structure protein belonging to the cytospin-A family, that may play a role in nuclear function during cell division. It is also highly expressed in certain tumor cell lines, suggesting that it may serve as a good tumor marker. It was was cloned as part of a chromosomal translocation involving PDGFRB in a case of juvenile myelomonocytic leukemia.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in testis. Barely detectablein other tissues. Also highly expressed in some cancer cell lines.

DISEASE:
Note=A chromosomal aberration involving CYTSB may be acause of juvenile myelomonocytic leukemia. Translocationt(5;17)(q33;p11.2) with PDGFRB.

Similarity:
Belongs to the cytospin-A family.
Contains 1 CH (calponin-homology) domain.

Database links:

Entrez Gene: 92521 Human

Omim: 608793 Human

SwissProt: Q5M775 Human

Unigene: 431045 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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