Rabbit Anti-MND1/FITC Conjugated antibody

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GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of antibody; Meiotic nuclear division protein 1 homolog; Meiotic nuclear divisions 1 homolog (S. cerevisiae); Meiotic nuclear divisions 1 homolog; MGC134110; MND1; RGD1

Cat:

SL7799R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human GAJ/MND1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

24kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.

Function:
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.

Subunit:
Heterodimer with PSMC3IP/HOP2. MND1-PSMC3IP interacts with DMC1 and RAD51 and binds preferentially to dsDNA.

Subcellular Location:
Nucleus (Probable)

Similarity:
Belongs to the MND1 family.

Database links:
UniProtKB/Swiss-Prot: Q9BWT6.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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