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Rabbit Anti-DSN1/FITC Conjugated antibody
background:
This gene encodes a kinetochore protein that functions aspart of the minichromosome instability-12 centromere complex. Theencoded protein is required for proper kinetochore assembly andprogression through the cell cycle. Alternative splicing results inmultiple transcript variants. [provided by RefSeq, Feb 2009].
Function:
Part of the MIS12 complex which is required for normalchromosome alignment and segregation and kinetochore formationduring mitosis.
Subunit:
Component of the MIS12 complex composed of MIS12, DSN1,NSL1 and PMF1. Also interacts with CASC5, CBX3 and CBX5.
Subcellular Location:
Nucleus. Chromosome, centromere,kinetochore.
Database links:
Entrez Gene: 79196 Human
Omim: 609175 Human
SwissProt: Q9H410 Human
Unigene: 632268 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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