Home > Product > Antibody > Rabbit Anti-DSN1/FITC Conjugated antibody
C20orf172; dJ469A13.2; DSN1; DSN1, MIND kinetochore complex component, homolog; DSN1, MIND kinetochore complex component, homolog (S. cerevisiae); DSN1_HUMAN; FLJ13346; Kinetochore associated protein DSN1; Kinetochore associated protein DSN1 homolog; Kine
Cat:
SL7796R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,Dog,Cow,)
Immunogen:
KLH conjugated synthetic peptide derived from human DSN1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
40kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a kinetochore protein that functions aspart of the minichromosome instability-12 centromere complex. Theencoded protein is required for proper kinetochore assembly andprogression through the cell cycle. Alternative splicing results inmultiple transcript variants. [provided by RefSeq, Feb 2009].

Function:
Part of the MIS12 complex which is required for normalchromosome alignment and segregation and kinetochore formationduring mitosis.

Subunit:
Component of the MIS12 complex composed of MIS12, DSN1,NSL1 and PMF1. Also interacts with CASC5, CBX3 and CBX5.

Subcellular Location:
Nucleus. Chromosome, centromere,kinetochore.

Database links:

Entrez Gene: 79196 Human

Omim: 609175 Human

SwissProt: Q9H410 Human

Unigene: 632268 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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