Rabbit Anti-ccnb1ip1/FITC Conjugated antibody

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C14orf18; CCNB1IP1; Chromosome 14 open reading frame 18; CIP1_HUMAN; Cyclin B1 interacting protein 1; Cyclin-B1-interacting protein 1; E3 ubiquitin-protein ligase CCNB1IP1; Enhancer of invasion 10; HEI10; Human enhancer of invasion 10.

Cat:

SL7784R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human ccnb1ip1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

32kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.
Tissue specificity: Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.

Function:
E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Subunit:
Binds CCNB1 and UBE2L3.

Subcellular Location:
Nucleus. Chromosome. Note=May associate with segregating chromosomes during metaphase and anaphase.

Tissue Specificity:
Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.

Post-translational modifications:
Ubiquitinated; autoubiquitinated.
Phosphorylated by CDK1 on serine or threonine residues (in vitro).

Similarity:
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 57820 Human

Omim: 608249 Human

SwissProt: Q9NPC3 Human

Unigene: 107003 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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