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Rabbit Anti-DCTN3/FITC Conjugated antibody
background:
Together with dynein may be involved in spindle assembly and cytokinesis.
Tissue specificity:Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Function:
ogether with dynein may be involved in spindle assembly and cytokinesis.
Subunit:
Subunit of dynactin, a multiprotein complex associated with dynein.
Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
Tissue Specificity:
Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Similarity:
Belongs to the dynactin subunit 3 family.
Database links:
Entrez Gene: 11258 Human
Entrez Gene: 53598 Mouse
Entrez Gene: 362504 Rat
Omim: 607387 Human
SwissProt: O75935 Human
SwissProt: Q9Z0Y1 Mouse
Unigene: 511768 Human
Unigene: 29025 Mouse
Unigene: 2038 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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