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Rabbit Anti-CAPD3/FITC Conjugated antibody
background:
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4. hCAP-D3 is a regulatory non-SMC subunit of the condensin II complex.
Function:
Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.
Subunit:
Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2.
Subcellular Location:
Nucleus.
Similarity:
Contains 4 HEAT repeats.
Database links:
Entrez Gene: 23310 Human
Omim: 609276 Human
SwissProt: P42695 Human
Unigene: 438550 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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