background:
Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Note=Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.
Similarity:
Belongs to the BOD1 family.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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