Home > Product > Antibody > Rabbit Anti-GANP/FITC Conjugated antibody
80 kDa MCM3 associated protein; 80 kDa MCM3-associated protein; Germinal center associated nuclear protein; KIAA0572; MAP80; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein; MCM3 minichromosome maintenan
Cat:
SL6383R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human GANP
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
218kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.

Function:
May be involved in the nuclear localization pathway of MCM3.

Subunit:
nteracts with MCM3.

Subcellular Location:
Cytoplasm. Nucleus

Similarity:
Belongs to the SAC3 family.

Database links:
UniProtKB/Swiss-Prot: O60318.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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