Rabbit Anti-FIS1/FITC Conjugated antibody

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CGI 135; CGI135; FIS 1; FIS1; Fis1 homolog; FIS1, S. cerevisiae, homolog of; FIS1_HUMAN; Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); Fission 1 (mitochondrial outer membrane) homolog (yeast); Fission 1 (mitochondrial outer membrane) h

Cat:

SL7646R-FITC

Species Reactivity：

Human,Rat,(predicted: Mouse,Dog,Pig,Cow,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human FIS1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Function:
Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Subunit:
Interacts with DNM1L/DLP1 through the TPR region. Interacts with MARCH5. Interacts with MID51.

Subcellular Location:
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.

Post-translational modifications:
Ubiquitinated by MARCH5.

Similarity:
Belongs to the FIS1 family.
Contains 1 TPR repeat.

Database links:

Entrez Gene: 51024 Human

Entrez Gene: 66437 Mouse

Entrez Gene: 288584 Rat

Omim: 609003 Human

SwissProt: Q9Y3D6 Human

SwissProt: Q9CQ92 Mouse

SwissProt: P84817 Rat

Unigene: 423968 Human

Unigene: 25849 Mouse

Unigene: 1298 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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