Home
>
Product
>
Antibody
>
Rabbit Anti-ACSM3/FITC Conjugated antibody
background:
ACSM3 is a 586 amino acid protein has a broad substrate specificity and utilizes magnesium as a cofactor. The gene encoding ACSM3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Function:
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro)
Subcellular Location:
Mitochondrion matrix
Similarity:
Belongs to the ATP-dependent AMP-binding enzyme family.
Database links:
Entrez Gene: 6296 Human
Entrez Gene: 20216 Mouse
Omim: 145505 Human
SwissProt: Q53FZ2 Human
SwissProt: Q3UNX5 Mouse
Unigene: 706754 Human
Unigene: 334199 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|