background:
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].
Function:
May play an important role in mediating p53/TP53-dependent apoptosis.
Subcellular Location:
Mitochondrion.
Tissue Specificity:
Only found to be expressed in thymus.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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