Rabbit Anti-PAICS/FITC Conjugated antibody

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ADE2; ADE2H1; AIR carboxylase; AIRC; DKFZp781N1372; MGC1343; MGC5024; Paics; PAIS; Phosphoribosylaminoimidazole carboxylase; PUR6_HUMAN; SAICAR synthetase.

Cat:

SL6369R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human PAICS

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

47kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its SLCterminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Subunit:
Homooctamer.

Similarity:
In the N-terminal section; belongs to the SAICAR synthetase family.
In the SLCterminal section; belongs to the AIR carboxylase family.

Database links:

Entrez Gene: 10606 Human

Entrez Gene: 67054 Mouse

Entrez Gene: 140946 Rat

Omim: 172439 Human

SwissProt: P22234 Human

SwissProt: Q9DCL9 Mouse

SwissProt: P51583 Rat

Unigene: 518774 Human

Unigene: 709570 Human

Unigene: 182931 Mouse

Unigene: 431705 Mouse

Unigene: 3015 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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