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Rabbit Anti-LANPL/FITC Conjugated antibody
background:
Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity.
Tissue specificityExpressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney.
Function:
Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity.
Subcellular Location:
Cytoplasm. Nucleus.
Tissue Specificity:
Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney.
Post-translational modifications:
Phosphorylated. The phosphorylation is nuclear localization signal (NLS)-dependent.
Similarity:
Belongs to the ANP32 family.
Contains 4 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Database links:
Entrez Gene: 81611 Human
Entrez Gene: 66471 Mouse
Entrez Gene: 361999 Rat
Omim: 609611 Human
SwissProt: Q9BTT0 Human
SwissProt: P97822 Mouse
SwissProt: Q5XIE0 Rat
Unigene: 656466 Human
Unigene: 218657 Mouse
Unigene: 4268 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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