Rabbit Anti-FEM1A/FITC Conjugated antibody

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EPRAP; Fem-1 homolog a (C. elegans); Fem1 homolog a; FEM1-alpha-A; FEM1a-A; Fem1aa; Feminization 1 homolog a (C. elegans); Feminization 1 homolog a; Prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; Protein fem-1 homolog A-A; FEM1A_H

Cat:

SL6861R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human FEM1A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

74kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
FEM1A is a caspase substrate homologous to the C. Elegans sex determining protein, FEM-1. Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Overexpression of FEM1A in mammalian cells is reported to induce apoptosis.

Function:
Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4.

Subunit:
Component of some E3 ubiquitin-protein ligase complex. Interacts with PTGER4.

Subcellular Location:
Cytoplasm (Probable).

Tissue Specificity:
Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).

Similarity:
Belongs to the fem-1 family.
Contains 9 ANK repeats.
Contains 2 TPR repeats.

Database links:

Entrez Gene: 516550 Cow

Entrez Gene: 55527 Human

Entrez Gene: 14154 Mouse

Entrez Gene: 316131 Rat

GenBank: NP_061178.1 Human

SwissProt: Q29RM5 Cow

SwissProt: Q9BSK4 Human

SwissProt: Q8C4V3 Mouse

SwissProt: Q4V890 Rat

Unigene: 515082 Human

Unigene: 290813 Mouse

Unigene: 228392 Rat

Unigene: 97265 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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