background:
BMP11 is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. BMP11 is a secreted signal that acts globally to specify positional identity along the anterior/ posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Function:
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Secreted (Probable).
Similarity:
Belongs to the TGF-beta family.
Database links:
UniProtKB/Swiss-Prot: O95390.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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