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Rabbit Anti-VIP Receptor 1/FITC Conjugated antibody
background:
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.
Tissue specificity:In lung, HT29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and Tsup-1, but not in the T-cell lines PEER, MOLT-4, HSB and YT.
Subcellular Location:
Cytoplasm. Nucleus.
Tissue Specificity:
Down-regulated in various cancer tissues.
Similarity:
Contains 1 GST SLCterminal domain.
Database links:
Entrez Gene: 7433 Human
Omim: 192321 Human
SwissProt: P32241 Human
Unigene: 348500 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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