Rabbit Anti-IEX1/FITC Conjugated antibody

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IEX1; PRG1; Anti death protein; Differentiation dependent gene 2 protein; DIF 2; DIF2; Differentiation dependent gene 2; Differentiation dependent gene 2 protein; Differentiation-dependent gene 2 protein; Expressed in pancreatic carcinoma; GLY 96; GLY96;

Cat:

SL6168R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008].

Function:
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival.

Subunit:
Interacts with the PPP2R5SLCPP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the IER3 family.

Database links:

Entrez Gene: 8870 Human

Entrez Gene: 15937 Mouse

Omim: 602996 Human

SwissProt: P46695 Human

SwissProt: P46694 Mouse

Unigene: 730861 Human

Unigene: 76095 Human

Unigene: 25613 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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